Many of these functions ended up described to take place through or Soon after sexual activity, and some were described to manifest Soon following the use of VIAGRA with no sexual exercise. Other folks were being noted to possess happened several hours to days right after the use of VIAGRA and sexual activity. It really is not possible to determine regardless of whether these activities are connected directly to VIAGRA, to sexual activity, to the patient's fundamental cardiovascular disease, to a combination of these aspects, or to other aspects [see WARNINGS AND PRECAUTIONS and Affected person Details].
The inhibition of PDE5 in A few of these tissues by sildenafil would be the foundation for the improved platelet antiaggregatory activity of NO noticed in vitro, an inhibition of platelet thrombus formation in vivo and peripheral arterial-venous dilatation in vivo.
Using VIAGRA gives no security against sexually transmitted health conditions. Counseling of patients in regards to the protective steps necessary to guard towards sexually transmitted conditions, such as the Human Immunodeficiency Virus (HIV), may be viewed as.
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Although the conversation between other protease inhibitors and sildenafil hasn't been researched, their concomitant use is predicted to boost sildenafil concentrations.
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Clients that have endured a myocardial infarction, stroke, or life-threatening arrhythmia within the previous six months;
unexpected Listening to lower or hearing decline. A number of people may possibly also have ringing in their ears (tinnitus) or dizziness. When you've got these indications, halt getting VIAGRA and phone a health care provider instantly.
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